Students Staff

Academic Staff

Dr Giovanni Stracquadanio

Staff positionLecturer
Telephone01206 872342

High-­throughput omic technologies are generating big­ data useful to address a number of biological and clinical questions. Recent advances in DNA synthesis methods provide unprecedented opportunities to integrate this omic information into synthetic systems to test hypotheses in ­vivo.

I am working on computational methods to design and analyse genomic information, aiming at understanding its role in fundamental biological processes and disease. To do this, I develop approaches, ranging from evolutionary optimization to statistical modelling and network analysis.

I obtained a Ph.D. in computer science from the University of Catania in Italy. From 2010, I was a postdoctoral fellow at Johns Hopkins University, working on the synthetic yeast project (Sc2.0), and later at the University of Oxford, focusing on cancer genetics. Currently, I am Lecturer at the School of Computer Science and Electronic Engineering.

  • 2010 - Ph.D. in Computer Science, University of Catania, Italy
  • 2006 - M.Sc. in Computer Science, University of Catania, Italy. Summa cum laude
Current research
  • Computer Aided Design methods for genome scale engineering
  • Polymer physics of synthetic chromosome looping
  • Network analysis and integration of proteomics data
  • Evolutionary optimization
Research interests
  • Computational Biology
  • Synthetic biology
  • Bioinformatics
  • Evolutionary algorithms
  • Global optimization
  • Network theory
  • Statistical mechanics
Teaching responsibilities
  •  CE219 -  ICT Systems Integration And Management


  • Computer Aided Design and Analysis Methods for Synthetic Genomics. Synthetic Genome Summer School. July 6, 2016. Edinburgh, UK
  • Polymorphisms in the p53 Pathway are Enriched in Cancer Susceptibility Loci and Share Characteristics with Somatic Pathway Mutations. 31st Genes & Cancer Conference. April 13, 2015. Cambridge, UK
  • Computational Challenges in Synthetic Biology. Synthetic Genomics Inc.. April 23, 2014. La Jolla, CA, USA
  • Computational Analysis and Validation of Structural Variations in Synthetic Yeast Genomes. 2nd International Conference on Computational Medicine. January 24, 2013. University of Florida. Gainesville, FL, USA
  • Design and Synthesis of Vitamin A in Yeast. NASA Workshop on Food Production in Space. September 20, 2012. NASA Ames Research Center, Mountain View, CA, USA
  • Structural Variation Analysis of a Synthetic Yeast Chromosome. Joint Genome Institute (JGI). September 18, 2012. Walnut Creek, CA, USA.

Additional information
  • 2016. Keystone Future of Science Scholarship. Keystone Genomics and Personalized Medicine Meeting, Banff, Canada
  • 2015. Best Poster Award. Cancer Research UK, Oxford, UK
  • 2015. Best postdoc talk prize at the 31st Genes & Cancer Conference. Nature Reviews Cancer, Cambridge, UK
  • 2012. AutoDesk IdeaStudio grant. AutoDesk Inc, CA, USA
  • 2011. Travel Award. Synthetic Biology 5.0, Stanford, CA, USA
  • 2009. Parallel Algorithms for Biological Pathways Analysis. HPC-Europa, UK
  • 2007. Travel Award. Synthetic Biology 3.0, ETH, Zurich, Switzerland
  • 2006-2009. Ph.D. Fellowship. Ministero dell'Istruzione, dell'Universita' e della Ricerca, Italy
  • 2001-2006. Scholarship for Excellent Student Career. Universita' degli Studi di Catania, Italy

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