BS131-4-AU-CO:
Biochemistry of Macromolecules

The details
2019/20
Life Sciences (School of)
Colchester Campus
Autumn
Undergraduate: Level 4
ReassessmentOnly
Thursday 03 October 2019
Saturday 14 December 2019
15
16 May 2019

 

Requisites for this module
(none)
(none)
(none)
(none)

 

BS230, BS281

Key module for

BSC C410 Genetics and Genomics,
BSC C411 Genetics and Genomics (Including Placement Year),
BSC C412 Genetics and Genomics (Including Year Abroad)

Module description

This module will investigate the structure and biochemistry of biologically-important macromolecules. The structure, function and evolution of proteins, and the properties of their building blocks, the amino acids will then be examined. Furthermore, how reversible binding of various ligand molecules to proteins relates to their biological role will be explored. The structures of the main carbohydrates of life, the polysaccharides, and the properties of their building blocks, the monosaccharides will then be examined. Finally, the structures and functions of the major types of lipids, i.e. triacylglycerols, phospholipids, sphingolipids and steroids, will be explored, particularly in relation to membrane structure and hormone action.

Module aims

The aim of this module is to investigate the structure and biochemistry of biologically important macromolecules. The course also aims to illustrate some basic experimental techniques used in biochemistry and offers students the opportunity to gain experience of a range of equipment and computer software.

Module learning outcomes

In order to pass this module, students will need to be able to:

1. describe the key structural features of proteins and explain how protein structure relates to function;
2. outline the basic principles of protein structural evolution;
3. describe how ligand-binding equilibria may form the basis of diverse biological phenomena;
4. describe the structures and functions of the major types of carbohydrates and lipids;
5. demonstrate competence in the analysis and interpretation of data, b) written communication, c) biochemical methodology and d) calculation of biochemical parameters.

Employability and Transferable Skills:

data analysis, interpretation and presentation
use of column chromatography for the separation of proteins
measure UV-VIS absorbance of protein samples using a spectrophotometer
prepare reagents following protocols
perform titrations
• estimate single-substrate enzyme kinetic values



Module information

No additional information available.

Learning and teaching methods

24 x 1 hour lectures plus 1 revision class before MCQ and 1 revision class before summer exam; 3 x 3 hour practicals

Bibliography

  • Nelson, David L.; Lehninger, Albert L.; Cox, Michael M. (2017) Lehninger Principles of biochemistry, Basingstoke: Macmillan Higher Education.

The above list is indicative of the essential reading for the course. The library makes provision for all reading list items, with digital provision where possible, and these resources are shared between students. Further reading can be obtained from this module's reading list.

Assessment items, weightings and deadlines

Coursework / exam Description Deadline Weighting
Coursework BS131 RESIT COURSEWORK – ONLY APPLICABLE TO STUDENTS UNDERTAKING SUMMER REASSESSMENT
Exam 50 minutes during Early Exams (Multiple Choice)
Exam 60 minutes during Summer (Main Period) (Main)

Overall assessment

Coursework Exam
33% 67%

Reassessment

Coursework Exam
33% 67%
Module supervisor and teaching staff
Dr Filippo Prischi, Dr Gareth Jones
School Undergraduate Office, email: bsugoffice (Non essex users should add @essex.ac.uk to create the full email address)

 

Availability
Yes
No
No

External examiner

Dr Clive Butler
The University of Exeter
Associate Professor of Microbial Biochemistry
Resources
Available via Moodle
Of 320 hours, 66 (20.6%) hours available to students:
254 hours not recorded due to service coverage or fault;
0 hours not recorded due to opt-out by lecturer(s).

 

Further information
Life Sciences (School of)

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