BS238-5-SP-CO:
Cell Biology and Cellular Pathology
2024/25
Life Sciences (School of)
Colchester Campus
Spring
Undergraduate: Level 5
Current
Monday 13 January 2025
Friday 21 March 2025
15
08 March 2024
Requisites for this module
(none)
(none)
(none)
(none)
BS349
BSC B990 Biomedical Science,
BSC B991 Applied Biomedical Science (NHS placement),
BSC B995 Biomedical Science (Including Year Abroad),
BSC B999 Biomedical Science (Including Placement Year),
BSC BD00 Biomedical Science (Including Foundation Year),
MSCIB099 Biomedical Science,
MSCIBA99 Biomedical Science (Including Placement Year),
MSCIBB99 Biomedical Science (Including Year Abroad)
This module begins with the ultrastructure of the nucleus before reviewing the role of the cytoskeleton in cellular and subcellular movement and in the determination of cell shape. It will also look at how cells communicate and explore the range of cytoplasmic signal transduction pathways.
The second half of the course will focus on the cellular changes that result in cancer development, and will examine a variety of different cancers, including breast, cervical, colorectal and lymphomas. This will include diagnosis, prognosis, ethics of screening and regulations involving collection and storage of tissue samples. The regulation of cell division and cell death is critical for the normal development of multicellular organisms and for tissue maintenance in the adult and the loss of regulation of these processes ultimately leads to cancer.
This aim of this module is:
- To provide a detailed view of human cell structure and function as a basis to explore the principles of cellular pathology.
By the end of this module, students will be expected to be able to:
- Describe methods for protein purification.
- Describe the turnover of enzymes both mechanistically and kinetically.
- Perform calculations to quantify enzymatic activities.
- Describe the clinical importance of the metabolism of calcium and lipids.
- Discuss the functions of the liver and kidney and describe the biology of diseases that affect these organs.
- Discuss the use of therapeutic drug monitoring in Biomedical Science.
- Perform biochemical assays in the laboratory.
No additional information available.
20 x 1 hour lectures
12 hours practical sessions
2 hours revision
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Institute of Biomedical Science (Great Britain) (2022)
Biomedical science practice: experimental & professional skills. Third edition. Edited by N. Ahmed, H. Glencross, and Q. Wang. Oxford: Oxford University Press. Available at:
https://app.kortext.com/Shibboleth.sso/Login?entityID=https://idp0.essex.ac.uk/shibboleth&target=https://app.kortext.com/borrow/2074569.
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Blann, A. (2015) ‘Cells of the cardiovascular and lymphatic systems’, in G. Orchard and B. Nation (eds)
Cell structure & function. Oxford: Oxford University Press, pp. 263–295. Available at:
https://app.kortext.com/Shibboleth.sso/Login?entityID=https://idp0.essex.ac.uk/shibboleth&target=https://app.kortext.com/borrow/190686/.
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Evans, D. and Robinson, M. (2018) ‘What is histopathology?’, in G. Orchard and B. Nation (eds)
Histopathology. Second edition. Oxford: Oxford University Press, pp. 1–33. Available at:
https://app.kortext.com/Shibboleth.sso/Login?entityID=https://idp0.essex.ac.uk/shibboleth&target=https://app.kortext.com/borrow/290314.
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Orchard, G. and Javed, A. (2018) ‘Immunocytochemistry in diagnostic histopathology’, in G. Orchard and B. Nation (eds)
Histopathology. Second edition. Oxford: Oxford University Press, pp. 170–203. Available at:
https://app.kortext.com/Shibboleth.sso/Login?entityID=https://idp0.essex.ac.uk/shibboleth&target=https://app.kortext.com/borrow/290314.
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Orchard, G. and Nation, B. (eds) (2015a) ‘Breast tissue’, in
Cell structure & function. Oxford: Oxford University Press, pp. 478–481. Available at:
https://app.kortext.com/Shibboleth.sso/Login?entityID=https://idp0.essex.ac.uk/shibboleth&target=https://app.kortext.com/borrow/190686.
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Orchard, G. and Nation, B. (eds) (2015c) ‘Skin and Breast’, in
Cell structure & function. Oxford: Oxford University Press, pp. 451–478. Available at:
https://app.kortext.com/Shibboleth.sso/Login?entityID=https://idp0.essex.ac.uk/shibboleth&target=https://app.kortext.com/borrow/190686.
The above list is indicative of the essential reading for the course.
The library makes provision for all reading list items, with digital provision where possible, and these resources are shared between students.
Further reading can be obtained from this module's
reading list.
Assessment items, weightings and deadlines
Coursework / exam |
Description |
Deadline |
Coursework weighting |
Coursework |
Prac 1 - Moodle Quiz |
|
7.1% |
Coursework |
Prac 2 - SPF |
|
50% |
Coursework |
Prac 3 (Lymph) Moodle Quiz |
|
3.6% |
Coursework |
Prac 4 |
|
3.6% |
Coursework |
Achieve Online Assessment |
|
7.1% |
Coursework |
Case Study |
|
28.6% |
Exam |
Main exam: In-Person, Closed Book, 120 minutes during Summer (Main Period)
|
Exam |
Reassessment Main exam: In-Person, Closed Book, 120 minutes during September (Reassessment Period)
|
Exam format definitions
- Remote, open book: Your exam will take place remotely via an online learning platform. You may refer to any physical or electronic materials during the exam.
- In-person, open book: Your exam will take place on campus under invigilation. You may refer to any physical materials such as paper study notes or a textbook during the exam. Electronic devices may not be used in the exam.
- In-person, open book (restricted): The exam will take place on campus under invigilation. You may refer only to specific physical materials such as a named textbook during the exam. Permitted materials will be specified by your department. Electronic devices may not be used in the exam.
- In-person, closed book: The exam will take place on campus under invigilation. You may not refer to any physical materials or electronic devices during the exam. There may be times when a paper dictionary,
for example, may be permitted in an otherwise closed book exam. Any exceptions will be specified by your department.
Your department will provide further guidance before your exams.
Overall assessment
Reassessment
Module supervisor and teaching staff
Dr Angela Pine, email: acpine@essex.ac.uk.
Dr Tim Barrow, Dr Greg Brooke, NHS Staff
School Undergraduate Office, email: bsugoffice (Non essex users should add @essex.ac.uk to create the full email address)
No
No
No
No external examiner information available for this module.
Available via Moodle
Of 30 hours, 21 (70%) hours available to students:
9 hours not recorded due to service coverage or fault;
0 hours not recorded due to opt-out by lecturer(s), module, or event type.
* Please note: due to differing publication schedules, items marked with an asterisk (*) base their information upon the previous academic year.
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