Protein Bioinformatics

The details
Life Sciences (School of)
Colchester Campus
Undergraduate: Level 5
Thursday 03 October 2019
Saturday 14 December 2019
17 May 2019


Requisites for this module



Key module for

BSC C700 Biochemistry,
BSC C701 Biochemistry (Including Placement Year),
BSC C703 Biochemistry (Including Year Abroad),
BSC CR00 Biochemistry (Including Foundation Year)

Module description

The post-genome era has seen significant advances in our ability to obtain biological data, be it protein sequences or structures. Bioinformatics have become an indispensible skill for the next generation of biochemists and biologists in order to retrieve, analyse and interpret data. This module will focus on how to decode the role and the molecular evolution of a protein starting from its sequence. The lectures will teach the theory and the computer practicals will introduce some of the many computer and web resources available to perform bioinformatics analyses.

Module aims

This module will introduce the different resources and tools available on-line for the study of protein structure and interaction.

Module learning outcomes

In order to pass this module the student will need to be able to:

1. use and retrieve information from protein databases and protein portals;
2. align protein sequences, and edit them in the light of amino acid similarities;
3. predict protein secondary and tertiary structure and protein-protein interaction;
4. observe and modify protein structure files using PyMol;
5. use webtools to recognise motifs in a protein sequence;
6. define the principles of molecular dynamics and perform energy minimisation.

Module information

No additional information available.

Learning and teaching methods

1 hour lecture and 2 hour workshop


This module does not appear to have a published bibliography.

Assessment items, weightings and deadlines

Coursework / exam Description Deadline Weighting
Coursework   Worksheet 1  15/11/2019  30% 
Coursework   Worksheet 2  13/12/2019  30% 
Practical   Problem Solving Test  17/01/2020  40% 

Overall assessment

Coursework Exam
100% 0%


Coursework Exam
100% 0%
Module supervisor and teaching staff
Dr Filippo Prischi, email:
Dr Filippo Prischi, Prof Chris Reynolds, Dr Radu Zabet
School Undergraduate Office, email: bsugoffice (Non essex users should add to create the full email address)



External examiner

Dr Clive Butler
The University of Exeter
Associate Professor of Microbial Biochemistry
Available via Moodle
Of 31 hours, 27 (87.1%) hours available to students:
4 hours not recorded due to service coverage or fault;
0 hours not recorded due to opt-out by lecturer(s).


Further information
Life Sciences (School of)

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