Clinical Biochemistry

The details
Life Sciences (School of)
Colchester Campus
Undergraduate: Level 5
Thursday 03 October 2019
Saturday 14 December 2019
21 May 2019


Requisites for this module



Key module for

BSC B990 Biomedical Science,
BSC B991 Applied Biomedical Science (NHS placement),
BSC B995 Biomedical Science (Including Year Abroad),
BSC B999 Biomedical Science (Including Placement Year),
BSC BD00 Biomedical Science (Including Foundation Year)

Module description

This course will first consider the mechanisms and kinetics of hydrolytic enzymes. Methods for protein analysis and purification will then be described, leading to a discussion of the use of recombinant DNA technology in the large scale production of proteins in the laboratory. The second part of the course involves study of the importance of lipids, carbohydrates and hormones in health and the diagnosis of disease. The use of antigens and metabolites as markers of disease will also be discussed.

Module aims

The aim of this module is to for you to discover the importance of enzymes on human health

Module learning outcomes

At the end of this module students will be able to:

1. describe methods for protein purification;
2. describe the turnover of enzymes both mechanistically and kinetically;
3. perform calculations to quantify enzymatic activities;
4. describe the clinical importance of the metabolism of calcium and lipids;
5. discuss the functions of the liver and kidney and describe the biology of diseases that affect these organs;
6. discuss the use of therapeutic drug monitoring in Biomedical Science;
7. perform biochemical assays in the laboratory.

Module information

No additional information available.

Learning and teaching methods

20 x 1 hour lectures 6 hours practicals 2 hours revision


  • Abubakar, MK; Wasagu, RSU; Umar, MI. (2013-08-01) 'Kinetic Studies of Alkaline Phosphatase from the Liver of Agama agama Lizard', in Nigerian Journal of Basic and Applied Sciences. vol. 21 (2)
  • Sharma, Ujjawal; Pal, Deeksha; Prasad, Rajendra. (2014-7) 'Alkaline Phosphatase: An Overview', in Indian Journal of Clinical Biochemistry. vol. 29 (3) , pp.269-278
  • (2017) Clinical biochemistry, Oxford: Oxford University Press.
  • Millán, José Luis. (2006-6) 'Alkaline Phosphatases', in Purinergic Signalling. vol. 2 (2) , pp.335-341
  • Luxton, R. (c2008) Clinical biochemistry, Bloxham: Scion.
  • Nelson, David L.; Lehninger, Albert L.; Cox, Michael M. (©2017) Lehninger Principles of biochemistry, Basingstoke: Macmillan Higher Education.
  • Chikezie, P.C.; Njoku, V.O.; Kaoje, M.A.; Monago, C.C.; Uwakwe, A.A. (2011-1-1) 'Kinetic Studies of Alkaline Phosphatase Extracted from Rabbit (Lepus townsendii) Liver', in Asian Journal of Biochemistry. vol. 6 (1) , pp.65-73

The above list is indicative of the essential reading for the course. The library makes provision for all reading list items, with digital provision where possible, and these resources are shared between students. Further reading can be obtained from this module's reading list.

Assessment items, weightings and deadlines

Coursework / exam Description Deadline Weighting
Coursework   Worksheet    30% 
Coursework   SPF (Group 1) - 5th Nov Prac Session    70% 
Exam  60 minutes during January (Multiple Choice) 
Exam  60 minutes during January (Main) 

Overall assessment

Coursework Exam
50% 50%


Coursework Exam
50% 50%
Module supervisor and teaching staff
Dr Paul Dobbin, email:
NHS Staff
School Undergraduate Office, email: bsugoffice (Non essex users should add to create the full email address)



External examiner

No external examiner information available for this module.
Available via Moodle
Of 102 hours, 21 (20.6%) hours available to students:
81 hours not recorded due to service coverage or fault;
0 hours not recorded due to opt-out by lecturer(s).


Further information
Life Sciences (School of)

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